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Leonard A Levin Selected Research

Optic Nerve Diseases (Optic Neuropathy)

11/2021Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma.
7/2018Neuroprotection in Optic Neuropathy.
1/2018Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B12-Deprivation Optic Neuropathy.
1/2017Neuroprotection in Glaucoma: Animal Models and Clinical Trials.
1/2017Translational Pharmacology in Glaucoma Neuroprotection.
1/2017Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative.
12/2015Reactive Oxygen Species in Mitochondrial Optic Neuropathies: Response.
6/2015Superoxide generation explains common features of optic neuropathies associated with cecocentral scotomas.
1/2012Optic nerve disease and axon pathophysiology.
9/2010Superoxide is an associated signal for apoptosis in axonal injury.
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Leonard A Levin Research Topics

Disease

14Optic Nerve Diseases (Optic Neuropathy)
11/2021 - 11/2003
9Glaucoma
11/2021 - 08/2005
6Optic Nerve Injuries
11/2018 - 04/2010
4Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy)
01/2017 - 03/2002
3Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy)
01/2019 - 01/2007
3Ganglion Cysts (Ganglion)
07/2010 - 01/2007
2Retinal Degeneration
11/2021 - 06/2012
2Wallerian Degeneration
09/2021 - 01/2017
2Neuroblastoma
01/2008 - 01/2007
2Wounds and Injuries (Trauma)
10/2005 - 09/2004
1Blister (Bulla)
09/2021
1Diabetic Retinopathy (Retinopathy, Diabetic)
01/2019
1Pain (Aches)
01/2019
1Chronic Disease (Chronic Diseases)
11/2018
1Vitamin B 12 Deficiency (Vitamin B12 Deficiency)
01/2018
1Malnutrition (Nutritional Deficiencies)
01/2018
1Scotoma (Scintillating Scotoma)
06/2015
1Burkitt Lymphoma (Burkitt's Lymphoma)
01/2015
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2015
1Melanoma (Melanoma, Malignant)
01/2015
1Retrograde Degeneration
07/2012
1Leukostasis
05/2010
1Neoplasms (Cancer)
03/2010
1Multiple Trauma (Multiple Injuries)
02/2008
1Alzheimer Disease (Alzheimer's Disease)
02/2008
1Erectile Dysfunction
11/2007
1Protein C Deficiency
02/2007
1Retinal Vein Occlusion
02/2007
1Peripheral Nerve Injuries
10/2005
1Glioma (Gliomas)
10/2005
1Giant Cell Arteritis (Horton Disease)
05/2005
1Friedreich Ataxia (Friedreich's Ataxia)
11/2003
1Ischemia
03/2002
1Vasculitis (Vasculitides)
03/2002

Drug/Important Bio-Agent (IBA)

7Retinaldehyde (Retinal)IBA
01/2019 - 08/2005
7Superoxides (Superoxide)IBA
01/2018 - 01/2007
3Mitochondrial DNA (mtDNA)IBA
01/2019 - 01/2007
2Neuroprotective AgentsIBA
11/2021 - 02/2008
2PhosphatidylserinesIBA
09/2021 - 01/2017
2Pharmaceutical PreparationsIBA
01/2019 - 02/2008
2DisulfidesIBA
01/2017 - 06/2012
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2017 - 03/2002
2StaurosporineIBA
01/2015 - 11/2007
1Sigma-1 ReceptorIBA
11/2021
1pridopidineIBA
11/2021
1CalciumIBA
09/2021
1PolyestersIBA
11/2018
1PolymersIBA
11/2018
1phosphine (phosphane)IBA
11/2018
1BoranesIBA
11/2018
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2018
1VitaminsIBA
01/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2015
1ArrestinIBA
06/2012
1Fluorescent Dyes (Fluorescent Probes)IBA
04/2012
1bis(3-propionic acid methyl ester)phenylphosphine borane complexIBA
09/2011
1Biomarkers (Surrogate Marker)IBA
09/2010
1Streptozocin (Streptozotocin)FDA Link
05/2010
15-chloromethylfluoresceinIBA
04/2010
1diacetylfluorescein (fluorescein diacetate)IBA
04/2010
17-hydroxystaurosporine (UCN 01)IBA
03/2010
1Memantine (Namenda)FDA Link
02/2008
1Glutamic Acid (Glutamate)FDA Link
01/2008
1RotenoneIBA
01/2008
1malic acid (malate)IBA
01/2008
1Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
01/2008
1Succinic Acid (Succinate)IBA
01/2008
1Antimycin AIBA
01/2008
1Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
11/2007
1Phosphodiesterase 5 InhibitorsIBA
11/2007
1Protein CIBA
02/2007
1AntigensIBA
02/2007
1Fluorescein (Funduscein)FDA LinkGeneric
02/2007
1LuciferasesIBA
10/2005
1Interleukin-6 (Interleukin 6)IBA
10/2005
1Ceruloplasmin (Ferroxidase)IBA
10/2005
1MetalsIBA
11/2003
1FrataxinIBA
11/2003
1AnticoagulantsIBA
03/2002
1Phenytoin (Dilantin)FDA LinkGeneric
03/2002
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
03/2002
1Oxygen (Dioxygen)IBA
03/2002

Therapy/Procedure

10Therapeutics
07/2018 - 03/2002
4Lasers (Laser)
01/2018 - 06/2010
2Axotomy
07/2012 - 09/2011
2Decompression
11/2007 - 03/2002
1Injections
01/2019
1Solid-State Lasers
07/2012